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Bullous pemphigoid in 65 years old female: a case report

I Dewa Made Rendy Sanjaya , Putu Artana, Embun Dini Hari

I Dewa Made Rendy Sanjaya
Faculty of Medicine, Udayana University, Bali-Indonesia. Email: rendy_rnz@yahoo.com

Putu Artana
Dermatology and Venereology Departement, Klungkung General Hospital, Bali-Indonesia

Embun Dini Hari
Dermatology and Venereology Departement, Klungkung General Hospital, Bali-Indonesia
Online First: July 09, 2019 | Cite this Article
Sanjaya, I., Artana, P., Hari, E. 2019. Bullous pemphigoid in 65 years old female: a case report. Bali Dermatology and Venereology Journal 1(2). DOI:10.15562/bdv.v1i2.7


Introduction: Bullous pemphigoid is an autoimmune disorder. The incidence of bullous pemphigoid has increased over time, current understanding regarding treatment and complication is an important issue considering the disease often occur in elderly resulting in high rates of morbidity to the patients. Aim of current case report is to describe the clinical relevance regarding symptom and treatment of bullous pemphigoid.

Case presentation: A 65 years old female patient, came with chief complaints of bullae in abdominal region with itching and burning sensation in the ruptured bullae. Over time bullae spread in lower and upper extremity. Patient was admitted for four days with therapy intravenous steroids, oral antihistamine, and potent topical steroids. Patient was discharged from hospital in well condition.

Conclusion: Bullous pemphigoid is an inflammatory autoimmune skin disease and usually result in good prognosis with adequate management.

Keywords: autoimmune, bullous, pemphigoid, skin, disease.

 

References

ACCEPTED MANUSCRIPT

Dreyer S, Aleshin M, Young L. Bullous pemphigoid localized in a primarily hemiplegic distribution. JAAD Case Reports. 2017;3:113-115.

Bagci IS, Horvath ON, Rucizka T, Sardy M. Bullous pemphigoid. Autoimmun Rev. 2017;16(5)445-455.

Baican A, Baican C, Chiriac G, Chiriac MT, Macovei V, Zillikens D, et al. Pemphigus vulgaris is the most common autoimmune bullous disease in Northwestern Romania. Int J Dermatol 2010 Jul;49:768-74.

Joly P, Baricault S, Sparsa A, Bernard P, Bédane C, Duvert-Lehembre S, et al. Incidence and mortality of bullous pemphigoid in France. J Invest Dermatol 2012;132:1998-2004.

Baum S, Sakka N, Artsi O, Trau H, Barzilai A. Diagnosis and classification of autoimmune blistering diseases. Autoimmun Rev 2014;13:482-9.

Di Zenzo G, Thoma-Uszynski S, Fontao L, Fontao L, Calabresi V, Hofmann SC, et al. Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid. Clin Immunol 2008;12:415-26.

Kushner C, Payne AS. Increasing the complement of therapeutic options in bullous pemphigoid. Jpournal of Investigative Dermatology. 2018;132(2):246-248.

Teruki D, Claw C, Kabashima K. IgG4, complement, and mechanism of blister formation in pemphigus and bullous pemphigoid. Journal of Dermatological Science; 2017;88(3):265-270.

Kershenovich R, Hodak M, Mimouni D. Diagnosis and classification of pemphigus and bullous pemphigoid. Autoimmunity Reviews. 2015;13(4):477-481.

Didona D, Zenzo DG. Humoral epitope spreading in autoimmune bullous disease. Front Immunol. 2018; 17(9):6-12.


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